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What led a 3-month-old boy to become covered in red skin lesions? That was the question facing Catherine Reilly, BS, of Georgetown University School of Medicine in Washington, D.C., and colleagues, as they report in JAMA Dermatologyopens in a new tab or window.

When the infant was referred for evaluation, clinicians learned that he showed multiple red skin papules at birth, and these increased in number and size during the next few months. The child's head and neck, trunk, arms and legs, right palm, mons pubis, and buttocks were affected. When the condition was at its most severe, there was 39 lesions, some of which were ulcerated and bleeding.

The child's birth at full-term and vaginal delivery had been unremarkable, and the birth mother did not receive prenatal care. Neither mother nor infant had any known exposure to hazardous substances. Regarding family medical history, the mother's was unknown, and the father's revealed nothing of note.