Washington, D.C., 9 June 2021 (PAHO/WHO) - Conducting health research with children is an ethical imperative that seeks to protect their well-being and advance their health and equitable treatment. An estimated 70% of the drugs regularly administered to children have not been studied with them. Thus, children's health is regularly jeopardized: When children are given drugs without evidence of their safety and efficacy in this specific population, they are exposed to risks. Such exposure is usually not preceded by an informed consent process. Children are exposed to risks as part of their medical care without any additional safeguards (such as close monitoring) and without the prospect of learning from these risks.

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https://www.paho.org/en/news/9-6-2021-should-health-research-be-conducted-children